Other articles where polyethylene glycol is discussed. Polyethylene glycol peg is an oligomer or polymer of ethylene oxide, with the. Polyethylene is a member of the important family of polyolefin resins. Effect of the molecular weight of polyethylene glycol core. Low density polyethylene ldpe high degree of short and long chain branching density 30. Peg is also known as polyethylene oxide peo or polyoxyethylene poe, depending on its molecular weight. Should unusual cramps, bloating, or diarrhea occur, consult your physician. Polypropylene glycol is produced, as an intermediate or a final product, by process units covered under this subpart. Polyethylene terephthalate production equipment cleaning cyanoacrylate and polyacrylonitrile.
Side effects, drug interactions, dosing, storage, and pregnancy and. National archives and records administrations electronic. The effect of polyethylene glycol peg coating on the magnetostructural properties and colloidal stability of co 0. In 1977, abuchowski and colleagues demonstrated that, as therapeutic agents, polyethylene glycol pegconjugated proteins are more effective than their corresponding unmodified parent molecules1. Safety of polyethylene glycol 3350 for the treatment of. Ethylene glycol is widely used to inhibit the formation of natural gas clathrates hydrates in long multiphase pipelines that convey natural gas from remote gas fields to a gas processing facility. Polyethylene glycol properties and the applications in.
Polyethylene oxide has also been shown to have mucoadhesive properties. Pdf the properties of the polyethylene glycol complex. How to use polyethylene glycol 3350 17 gramdose oral powder. Typical physical properties carbowax polyethylene glycol range of avg. If you are using polyethylene glycol 3350 from a bottle, use the measuring line on the bottle cap to measure a single dose about 1 heaping tablespoon. Polyethylene glycol peg is a hydrophilic polymer that may have neuroprotective properties such as aiding in repairing damaged axons kwon et al. The main factors responsible for the observed changes in the zeta. Polyethylene glycols and aqueous polyethylene glycol solutions can be sterilized by autoclaving, filtration or gamma irradiation. The polyethylene glycol samples had average molecular masses of 8000,3350. Polyethylene glycol is a component of the pegelectrolyte lavage solution that has been used in large volume to cleanse the gastrointestinal tract for diagnostic and surgical procedures in. Polyethylene glycol an overview sciencedirect topics. Ch3och2ch2noh where n is the average number of repeating oxyethylene groups.
Polyethylene glycol product number p 6667 store at room temperature product description general formula. These properties are important in the application of low molecular weight liquid peg as a solvent in chemical reactions. Effect of the molecular weight of poly ethylene glycol on the. Polyester resins are known for their excellent combination of. Crodas group of polyethylene glycols and polyol esters are now to be known under the below tradenames. Carefully introduce 25 ml of the phthalic anhydride solution into a clean, dry, heatresistant pressure bottle. Polyethylene terephthalate pet or pete is a generalpurpose thermoplastic polymer which belongs to the polyester family of polymers. Aqueous solutions of polyethylene glycol density and. Polyethylene glycols and polyol esters offer diverse properties for the formulation of a. Polyethylene polyethylenes are semicrystalline materials with excellent chemical resistance, good fatigue and wear resistance, and a wide range of properties due to differences in length of the. It starts with the physical properties and primary hydroxyl functionality of pegs and mpegs, which make them valuable formulating ingredients or. Polyethylene glycolconjugated pharmaceutical proteins. This usfdaapproved polymer is popular due to its tunable properties and wellestablished safety profile.
Carbowax polyethylene glycols are produced to meet the requirements for use under food. This is a brief description of the properties of the ethylene glycol for industrial porpouses. Polyethylene, light, versatile synthetic resin made from the polymerization of ethylene. Polyethylene glycol peg selection guide sigmaaldrich. It should always be taken by mouth after being dissolved in 48 ounces of water, juice, soda, coffee, or tea. Accordingly, the optical constants of peg should be a useful resource to other scientists.
Pdf physical properties of polyethylene glycol peg. Polyethylene glycol peg, also sometimes referred to as polyethylene oxide peo, is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications. Polyethylene glycol peg is a polymer of choice in drug delivery systems. Volume 10 polyethylene glycol 249 in the foodstuffs industry, e.
Polyethylene glycols are chemically stable in air and in solution although grades with a molecular weight less than 2000 are hygroscopic. The densities and viscosities of concentrated aqueous solutions of polyethylene glycol 1050 mass % have been measured. Pdf polyethylene glycol and solutions of polyethylene glycol as. Typical properties, not to be construed as specifications. Physical properties of triethylene glycol determined on purified samples of triethylene glycol the. Revision bulletin 2 propylene official february 1, 2010 ature is 250, and the column temperature is programmed at a rateprocedureinject a suitable volume, typically about 10 l, of of 5 per minute from 120 to 200, and helium is used as the car propylene glycol into a suitable gas chromatograph, and record the. Abstract the effect of the molecular weight of polyethylene glycol peg on the physical properties of waterbased magnetic fluids with sodium. Take by mouth usually once daily, or as directed by your doctor or the directions on the product package if you are prescribed the.
Sample preparation for liquid polyethylene glycols. Polyethylene glycol 3350 miralax, glycolax is a drug used to treat occasional constipation and for bowel preparation prior to procedures. Polyethylene glycol 25322683 no no no chemical weapons convention. Polyethylene glycols do not support microbial growth, nor do they become rancid. Polyethylene glycols are watersoluble liquids or waxy solids used in cosmetic and pharmaceutical preparations and in the manufacture of. Physical properties of polyethylene glycol pegbased. Rheological properties of polyethylene glycol solutions.